{"metadata":{"accession":"PF15866","entry_id":null,"type":"domain","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR031732","hierarchy":null,"name":{"name":"Domain of unknown function (DUF4729)","short":"DUF4729"},"description":[{"text":"<p>This family of proteins is functionally uncharacterised. This family of proteins is found in insects. Proteins in this family are typically between 238 and 666 amino acids in length. This domain has been identified as structurally similar to TRAF-like domains ([pfam:PF03145]) [[cite:PUB00152793]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"<p>A <b>domain of unknown function</b> (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.</p>","thumbnail":null}],"literature":{"PUB00152793":{"PMID":36419248,"ISBN":null,"volume":"32","issue":"1","year":2023,"title":"DALI shines a light on remote homologs: One hundred discoveries.","URL":null,"raw_pages":"e4519","medline_journal":"Protein Sci","ISO_journal":"Protein Sci","authors":["Holm L","Laiho A","Toronen P","Salgado M."],"DOI_URL":"https://doi.org/10.1002/pro.4519"}},"set_info":{"accession":"CL0389","name":"TRAF"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":9,"interactions":0,"matches":431,"pathways":0,"proteins":430,"proteomes":149,"sets":1,"structural_models":{"alphafold":369},"structures":0,"taxa":526},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":36,"alignment:full":251},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}