{"metadata":{"accession":"PF15851","entry_id":null,"type":"domain","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR031710","hierarchy":null,"name":{"name":"Domain of unknown function (DUF4723)","short":"DUF4723"},"description":[{"text":"<p>This domain is found in mammalian proteins. There are a number of conserved cysteines but it is unlikely to be a zinc-finger family. This entry includes PATE4 from mice. According to structure predictions (AlphaFold models and DALI server), this domain is structurally similar to members of the uPar/Lys6 domain superfamily.</p>","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"<p>A <b>domain of unknown function</b> (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.</p>","thumbnail":null}],"literature":null,"set_info":{"accession":"CL0117","name":"uPAR_Ly6_toxin"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":1,"interactions":0,"matches":104,"pathways":0,"proteins":104,"proteomes":84,"sets":1,"structural_models":{"alphafold":83},"structures":0,"taxa":308},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":1,"alignment:full":87},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}