{"metadata":{"accession":"PF15848","entry_id":null,"type":"family","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR031706","hierarchy":null,"name":{"name":"Odontogenesis associated phosphoprotein","short":"ODAPH"},"description":[{"text":"<p>This family is found in mammals. It includes odontogenesis associated phosphoprotein (ODAPH or in human C4orf26) which is expressed in the enamel organ of the tooth and may promote nucleation of  hydroxyapatite [[cite:PUB00087303]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00087303":{"PMID":22901946,"ISBN":null,"volume":"91","issue":"3","year":2012,"title":"Mutations in C4orf26, encoding a peptide with in vitro hydroxyapatite crystal nucleation and growth activity, cause amelogenesis imperfecta.","URL":null,"raw_pages":"565-71","medline_journal":"Am J Hum Genet","ISO_journal":"Am. J. Hum. Genet.","authors":["Parry DA","Brookes SJ","Logan CV","Poulter JA","El-Sayed W","Al-Bahlani S","Al Harasi S","Sayed J","Raif el M","Shore RC","Dashash M","Barron M","Morgan JE","Carr IM","Taylor GR","Johnson CA","Aldred MJ","Dixon MJ","Wright JT","Kirkham J","Inglehearn CF","Mighell AJ."],"DOI_URL":"https://doi.org/10.1016/j.ajhg.2012.07.020"}},"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":2,"interactions":0,"matches":138,"pathways":0,"proteins":137,"proteomes":114,"sets":0,"structural_models":{"alphafold":121},"structures":0,"taxa":393},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":7,"alignment:full":123},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}