{"metadata":{"accession":"PF15838","entry_id":null,"type":"domain","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR031684","hierarchy":null,"name":{"name":"LLLL and CFNLAS motif-containing protein 1","short":"LLCFC1"},"description":[{"text":"<p>LLCFC1 (also known as SOF1) and its homologues can be found in eukaryotes. They have two conserved sequence motifs: LLLL and CFNLAS. LLCFC1 is a sperm protein required for sperm-oocyte fusion in mice [[cite:PUB00094436]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00094436":{"PMID":32393636,"ISBN":null,"volume":"117","issue":"21","year":2020,"title":"Sperm proteins SOF1, TMEM95, and SPACA6 are required for sperm-oocyte fusion in mice.","URL":null,"raw_pages":"11493-11502","medline_journal":"Proc Natl Acad Sci U S A","ISO_journal":"Proc. Natl. Acad. Sci. U.S.A.","authors":["Noda T","Lu Y","Fujihara Y","Oura S","Koyano T","Kobayashi S","Matzuk MM","Ikawa M."],"DOI_URL":null}},"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":2,"interactions":0,"matches":176,"pathways":0,"proteins":174,"proteomes":158,"sets":0,"structural_models":{"alphafold":148},"structures":0,"taxa":553},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":9,"alignment:full":150},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}