{"metadata":{"accession":"PF15806","entry_id":null,"type":"domain","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR055453","hierarchy":null,"name":{"name":"TRAPP14 N-terminal","short":"TRAPP14_N"},"description":[{"text":"<p>This entry includes Trafficking protein particle complex subunit 14 (TRAPP14), a specific subunit of the TRAPP (transport protein particle) II complex, a conserved vesicle tethering complex that functions in late Golgi trafficking as a membrane tether [[cite:PUB00092767],[cite:PUB00096661]]. This entry represents the N-terminal region consisting of two domains which adopt a Ig-like fold, where distant amino acids in the sequence contribute to different beta-sheets in the structure.</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00096661":{"PMID":31467083,"ISBN":null,"volume":"294","issue":"42","year":2019,"title":"The C7orf43/TRAPPC14 component links the TRAPPII complex to Rabin8 for preciliary vesicle tethering at the mother centriole during ciliogenesis.","URL":null,"raw_pages":"15418-15434","medline_journal":"J Biol Chem","ISO_journal":"J Biol Chem","authors":["Cuenca A","Insinna C","Zhao H","John P","Weiss MA","Lu Q","Walia V","Specht S","Manivannan S","Stauffer J","Peden AA","Westlake CJ."],"DOI_URL":null},"PUB00092767":{"PMID":30715179,"ISBN":null,"volume":"142","issue":"3","year":2019,"title":"Mutations in the microtubule-associated protein MAP11 (C7orf43) cause microcephaly in humans and zebrafish.","URL":null,"raw_pages":"574-585","medline_journal":"Brain","ISO_journal":"Brain","authors":["Perez Y","Bar-Yaacov R","Kadir R","Wormser O","Shelef I","Birk OS","Flusser H","Birnbaum RY."],"DOI_URL":"https://doi.org/10.1093/brain/awz004"}},"set_info":{"accession":"CL0159","name":"E-set"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":21,"interactions":0,"matches":791,"pathways":0,"proteins":723,"proteomes":423,"sets":1,"structural_models":{"alphafold":612},"structures":0,"taxa":1453},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":6,"alignment:full":621},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}