{"metadata":{"accession":"PF15370","entry_id":null,"type":"family","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR027921","hierarchy":null,"name":{"name":"NOP protein chaperone 1","short":"NOPCHAP1"},"description":[{"text":"<p>This entry includes NOPCHAP1 from animals and New4 from fission yeast. NOPCHAP1 is a client-loading PAQosome/R2TP complex cofactor that selects NOP58 to promote box C/D small nucleolar ribonucleoprotein (snoRNP) assembly [[cite:PUB00097888]]. The function of New4 is not clear.</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00097888":{"PMID":33367824,"ISBN":null,"volume":"49","issue":"2","year":2021,"title":"NOPCHAP1 is a PAQosome cofactor that helps loading NOP58 on RUVBL1/2 during box C/D snoRNP biogenesis.","URL":null,"raw_pages":"1094-1113","medline_journal":"Nucleic Acids Res","ISO_journal":"Nucleic Acids Res","authors":["Abel Y","Paiva ACF","Bizarro J","Chagot ME","Santo PE","Robert MC","Quinternet M","Vandermoere F","Sousa PMF","Fort P","Charpentier B","Manival X","Bandeiras TM","Bertrand E","Verheggen C."],"DOI_URL":null}},"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":40,"interactions":0,"matches":2265,"pathways":0,"proteins":2264,"proteomes":1821,"sets":0,"structural_models":{"alphafold":1909},"structures":0,"taxa":5081},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":25,"alignment:full":1717},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}