{"metadata":{"accession":"PF15239","entry_id":null,"type":"family","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR029358","hierarchy":null,"name":{"name":"Cilia-and flagella-associated protein 96","short":"CFAP96-like"},"description":[{"text":"<p>This family (previously DUF4586) represents Cilia- and flagella-associated protein 96 (CFAP96, also known as C4orf47). CFAP96 is an axonemal microtubule-associated protein (MAP). The EM structure of sperm DMTs shows that CFAP96 binds to tubulin and, similarly to other axonemal wedge-MAPs, binds deeper into the inter-protofilament cleft making extensive contacts with flanking protofilaments [[cite:PUB00151496]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00151496":{"PMID":37327785,"ISBN":null,"volume":"186","issue":"13","year":2023,"title":"Structural specializations of the sperm tail.","URL":null,"raw_pages":"2880-2896.e17","medline_journal":"Cell","ISO_journal":"Cell","authors":["Leung MR","Zeng J","Wang X","Roelofs MC","Huang W","Zenezini Chiozzi R","Hevler JF","Heck AJR","Dutcher SK","Brown A","Zhang R","Zeev-Ben-Mordehai T."],"DOI_URL":"https://doi.org/10.1016/j.cell.2023.05.026"}},"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":21,"interactions":0,"matches":1376,"pathways":0,"proteins":1331,"proteomes":907,"sets":0,"structural_models":{"alphafold":1169},"structures":9,"taxa":3017},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":32,"alignment:full":1082},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}