{"metadata":{"accession":"PF15145","entry_id":null,"type":"family","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR028099","hierarchy":null,"name":{"name":"Domain of unknown function (DUF4577)","short":"DUF4577"},"description":[{"text":"<p>The function of this family of proteins, has not, as yet, been determined. Members of this family are as yet uncharacterised. This family of proteins is found in eukaryotes. Proteins in this family are typically 128 amino acids in length.</p>","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"<p>A <b>domain of unknown function</b> (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.</p>","thumbnail":null}],"literature":null,"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":6,"interactions":0,"matches":611,"pathways":0,"proteins":605,"proteomes":545,"sets":0,"structural_models":{"alphafold":572},"structures":0,"taxa":1606},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":7,"alignment:full":561},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}