{"metadata":{"accession":"PF15137","entry_id":null,"type":"family","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR029250","hierarchy":null,"name":{"name":"Exosomal polycystin 1 interacting protein","short":"ECPIP"},"description":[{"text":"<p>This family includes the exosomal polycystin 1 interacting protein (also known as C21orf62 or CU062 in human), which is a small glycoprotein that can oligomerize with itself and interact with PC1 protein polycystin-1 (PC1). It may have a role in the identification of senescent mitochondria and their extrusion in extracellular vesicles [[cite:PUB00153072]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00153072":{"PMID":37681898,"ISBN":null,"volume":"12","issue":"17","year":2023,"title":"Polycystin-1 Interacting Protein-1 (CU062) Interacts with the Ectodomain of Polycystin-1 (PC1).","URL":null,"raw_pages":"2166","medline_journal":"Cells","ISO_journal":"Cells","authors":["Lea WA","Winklhofer T","Zelenchuk L","Sharma M","Rossol-Allison J","Fields TA","Reif G","Calvet JP","Bakeberg JL","Wallace DP","Ward CJ."],"DOI_URL":"https://doi.org/10.3390/cells12172166"}},"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":4,"interactions":0,"matches":514,"pathways":0,"proteins":509,"proteomes":416,"sets":0,"structural_models":{"alphafold":442},"structures":0,"taxa":1407},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":12,"alignment:full":393},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}