{"metadata":{"accession":"PF15104","entry_id":null,"type":"family","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR029375","hierarchy":null,"name":{"name":"Cilia- and flagella-associated protein 141","short":"CFAP141"},"description":[{"text":"<p>This family includes Cilia- and flagella-associated protein 141 (CFAP141, also known as C1orf189 protein). Members of this family may be microtubule inner proteins (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating [[cite:PUB00100771]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00100771":{"PMID":34715025,"ISBN":null,"volume":"184","issue":"23","year":2021,"title":"De novo identification of mammalian ciliary motility proteins using cryo-EM.","URL":null,"raw_pages":"5791-5806.e19","medline_journal":"Cell","ISO_journal":"Cell","authors":["Gui M","Farley H","Anujan P","Anderson JR","Maxwell DW","Whitchurch JB","Botsch JJ","Qiu T","Meleppattu S","Singh SK","Zhang Q","Thompson J","Lucas JS","Bingle CD","Norris DP","Roy S","Brown A."],"DOI_URL":null}},"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":10,"interactions":0,"matches":433,"pathways":0,"proteins":432,"proteomes":370,"sets":0,"structural_models":{"alphafold":370},"structures":18,"taxa":1423},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":9,"alignment:full":353},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}