{"metadata":{"accession":"PF15072","entry_id":null,"type":"domain","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR058570","hierarchy":null,"name":{"name":"Homologous recombination OB-fold protein","short":"HROB"},"description":[{"text":"<p>This family represents Homologous recombination OB-fold protein (HROB). During homologous recombination, HROB acts by recruiting the MCM8-MCM9 helicase complex to sites of DNA damage to promote DNA repair synthesis [[cite:PUB00093964],[cite:PUB00093965]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00093965":{"PMID":31575675,"ISBN":null,"volume":"33","issue":"19-20","year":2019,"title":"Ways to unwind with HROB, a new player in homologous recombination.","URL":null,"raw_pages":"1293-1294","medline_journal":"Genes Dev","ISO_journal":"Genes Dev.","authors":["Saredi G","Rouse J."],"DOI_URL":null},"PUB00093964":{"PMID":31467087,"ISBN":null,"volume":"33","issue":"19-20","year":2019,"title":"Control of homologous recombination by the HROB-MCM8-MCM9 pathway.","URL":null,"raw_pages":"1397-1415","medline_journal":"Genes Dev","ISO_journal":"Genes Dev.","authors":["Hustedt N","Saito Y","Zimmermann M","Alvarez-Quilon A","Setiaputra D","Adam S","McEwan A","Yuan JY","Olivieri M","Zhao Y","Kanemaki MT","Jurisicova A","Durocher D."],"DOI_URL":null}},"set_info":{"accession":"CL0021","name":"OB"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":62,"interactions":0,"matches":2190,"pathways":0,"proteins":2185,"proteomes":1279,"sets":1,"structural_models":{"alphafold":1623},"structures":0,"taxa":4107},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":43,"alignment:full":1406},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}