"accession"	"counters"	"cross_references"	"description"	"entry_id"	"go_terms"	"hierarchy"	"integrated"	"is_llm"	"is_reviewed_llm"	"is_updated_llm"	"literature"	"member_databases"	"name"	"overlaps_with"	"representative_structure"	"set_info"	"source_database"	"type"	"wikipedia"
"PF14780"	"{'subfamilies': 0, 'domain_architectures': 29, 'interactions': 0, 'matches': 2500, 'pathways': 0, 'proteins': 2489, 'proteomes': 1616, 'sets': 1, 'structural_models': {'alphafold': 2260, 'bfvd': 0}, 'structures': 0, 'taxa': 5281}"	"{}"	"[{'text': '<p>This domain is found at the N-terminal of nucleolus and neural progenitor protein (NEPRO) which may play a role in cortex development as part of the Notch signalling pathway. Downstream of Notch may repress the expression of proneural genes and inhibit neuronal differentiation thereby maintaining neural progenitors [[cite:PUB00101272]]. NEPRO may also play a role in preimplentation embryo development [[cite:PUB00101273]]. NEPRO interacts with multiple protein subunits of RMRP and is implicated in Anauxetic dysplasia 3 [[cite:PUB00101274]]. NEPRO is likely the human orthologue of RMP1 subunit from yeast and they share a four-helix bundle domain structure.</p>', 'llm': False, 'checked': False, 'updated': False}]"	""	""	""	"IPR027951"	False	False	False	"{'PUB00101273': {'PMID': 26178919, 'ISBN': None, 'volume': '57', 'issue': '7', 'year': 2015, 'title': 'Nepro is localized in the nucleolus and essential for preimplantation development in mice.', 'URL': None, 'raw_pages': '529-38', 'medline_journal': 'Dev Growth Differ', 'ISO_journal': 'Dev Growth Differ', 'authors': ['Hashimoto M', 'Sato T', 'Muroyama Y', 'Fujimura L', 'Hatano M', 'Saito T.'], 'DOI_URL': None}, 'PUB00101274': {'PMID': 31250547, 'ISBN': None, 'volume': '179', 'issue': '9', 'year': 2019, 'title': 'An emerging ribosomopathy affecting the skeleton due to biallelic variations in NEPRO.', 'URL': None, 'raw_pages': '1709-1717', 'medline_journal': 'Am J Med Genet A', 'ISO_journal': 'Am J Med Genet A', 'authors': ['Narayanan DL', 'Shukla A', 'Kausthubham N', 'Bhavani GS', 'Shah H', 'Mortier G', 'Girisha KM.'], 'DOI_URL': None}, 'PUB00101272': {'PMID': 19906856, 'ISBN': None, 'volume': '136', 'issue': '23', 'year': 2009, 'title': 'Identification of Nepro, a gene required for the maintenance of neocortex neural progenitor cells downstream of Notch.', 'URL': None, 'raw_pages': '3889-93', 'medline_journal': 'Development', 'ISO_journal': 'Development', 'authors': ['Muroyama Y', 'Saito T.'], 'DOI_URL': None}}"	""	"{'name': 'Nucleolus and neural progenitor protein, N-terminal', 'short': 'NEPRO_N'}"	""	""	"{'accession': 'CL0732', 'name': 'RMP1-like'}"	"pfam"	"domain"	""