{"metadata":{"accession":"PF14737","entry_id":null,"type":"family","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR027974","hierarchy":null,"name":{"name":"Domain of unknown function (DUF4470)","short":"DUF4470"},"description":[{"text":"<p>This family is conserved from fungi to Metazoa and includes plants.  The function is not known, but several members have zinc-finger domain, zf-MYND, [pfam:PF01753], at their very C-terminus. Others are also associated with DUF1279, [pfam:PF06916].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"<p>A <b>domain of unknown function</b> (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.</p>","thumbnail":null}],"literature":null,"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":124,"interactions":0,"matches":3844,"pathways":0,"proteins":3822,"proteomes":1799,"sets":0,"structural_models":{"alphafold":3142},"structures":0,"taxa":5066},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":135,"alignment:full":3117},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}