{"metadata":{"accession":"PF14688","entry_id":null,"type":"family","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR027989","hierarchy":null,"name":{"name":"Domain of unknown function (DUF4461)","short":"DUF4461"},"description":[{"text":"<p>This domain family is found in eukaryotes, and is approximately 310 amino acids in length.</p>","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"<p>A <b>domain of unknown function</b> (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.</p>","thumbnail":null}],"literature":null,"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":28,"interactions":0,"matches":1755,"pathways":0,"proteins":1717,"proteomes":1217,"sets":0,"structural_models":{"alphafold":1528},"structures":1,"taxa":3983},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":31,"alignment:full":1374},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}