This family includes the B. subtilis YjgB protein [swissprot:O34960], which is functionally uncharacterised. This is not a homologue of E. coli YjgB, Swiss: P27250. Expression of B. subtilis YjgB is regulated by the alternative transcription factor sigma-B [[cite:PUB00057342]]. This family is found in bacteria, and is approximately 140 amino acids in length.
","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"A domain of unknown function (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.
","thumbnail":null}],"literature":{"PUB00057342":{"PMID":11532142,"ISBN":null,"volume":"41","issue":"4","year":2001,"title":"Genome-wide analysis of the general stress response in Bacillus subtilis.","URL":null,"raw_pages":"757-74","medline_journal":"Mol Microbiol","ISO_journal":"Mol. Microbiol.","authors":["Price CW","Fawcett P","Ceremonie H","Su N","Murphy CK","Youngman P."],"DOI_URL":"http://dx.doi.org/10.1046/j.1365-2958.2001.02534.x"}},"set_info":{"accession":"CL0320","name":"PepSY"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":21,"interactions":0,"matches":787,"pathways":0,"proteins":755,"proteomes":578,"sets":1,"structural_models":{"alphafold":458},"structures":1,"taxa":787},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":14,"alignment:full":396},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}