{"metadata":{"accession":"PF14146","entry_id":null,"type":"family","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR025426","hierarchy":null,"name":{"name":"Domain of unknown function (DUF4305)","short":"DUF4305"},"description":[{"text":"<p>This family includes the B. subtilis YdiK protein [swissprot:O05524], which is functionally uncharacterised.  This is not a homologue of E. coli YdiK, which belongs to [pfam:PF01594].  This family of proteins is found in bacteria. Proteins in this family are approximately 60 amino acids in length.</p>","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"<p>A <b>domain of unknown function</b> (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.</p>","thumbnail":null}],"literature":null,"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":1,"interactions":0,"matches":648,"pathways":0,"proteins":648,"proteomes":647,"sets":0,"structural_models":{"alphafold":416},"structures":0,"taxa":840},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":13,"alignment:full":301},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}