{"metadata":{"accession":"PF14111","entry_id":null,"type":"domain","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR025558","hierarchy":null,"name":{"name":"Domain of unknown function (DUF4283)","short":"DUF4283"},"description":[{"text":"<p>This domain family is found in plants, and is approximately 100 amino acids in length. Considering the very diverse range of other domains it is associated with it is possible that this domain is a binding/guiding region. There are two highly conserved tryptophan residues.</p>","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"<p>A <b>domain of unknown function</b> (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.</p>","thumbnail":null}],"literature":null,"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":1056,"interactions":0,"matches":23565,"pathways":0,"proteins":23437,"proteomes":339,"sets":0,"structural_models":{"alphafold":17164},"structures":0,"taxa":984},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":51,"alignment:full":14738},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}