This family of proteins is functionally uncharacterised. This family of proteins is found in bacteria, archaea and eukaryotes. Proteins in this family are typically between 95 and 124 amino acids in length. Structural models show this family adopts a structure found in bacterial toxins, suggesting this family are the toxins in a toxin-antitoxin system.
","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"A domain of unknown function (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.
","thumbnail":null}],"literature":null,"set_info":{"accession":"CL0136","name":"Plasmid_toxin"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":15,"interactions":0,"matches":1582,"pathways":0,"proteins":1582,"proteomes":1338,"sets":1,"structural_models":{"alphafold":1058},"structures":0,"taxa":2840},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":89,"alignment:full":926},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}