{"metadata":{"accession":"PF13870","entry_id":null,"type":"coiled_coil","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR025254","hierarchy":null,"name":{"name":"CCDC113/CCDC96, coiled-coil","short":"CCDC113_CCDC96_CC"},"description":[{"text":"<p>This entry represents the coiled-coil region of Coiled-coil domain-containing protein 113 (CCDC113, also known as cilia- and flagella-associated protein 263, CFAP263) and coiled-coil domain-containing protein 96 (CCDC96, also known as cilia- and flagella-associated protein 184, CFAP184) [[cite:PUB00159884],[cite:PUB00153410]]. These proteins form a complex and regulate ciliary beating that connects radial spoke 3 (RS3) to the inner dynein arm (IDA) and the nexin-dynein regulatory complex (N-DRC). The complex is positioned parallel to N-DRC and forms a connection between the arch at the base of RS3, the IDA tail and N-DRC [[cite:PUB00159884]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00159884":{"PMID":25074808,"ISBN":null,"volume":"127","issue":"Pt 19","year":2014,"title":"Proteomic analysis of mammalian sperm cells identifies new components of the centrosome.","URL":null,"raw_pages":"4128-33","medline_journal":"J Cell Sci","ISO_journal":"J Cell Sci","authors":["Firat-Karalar EN","Sante J","Elliott S","Stearns T."],"DOI_URL":"https://doi.org/10.1242/jcs.157008"},"PUB00153410":{"PMID":33661892,"ISBN":null,"volume":"17","issue":"3","year":2021,"title":"Ccdc113/Ccdc96 complex, a novel regulator of ciliary beating that connects radial spoke 3 to dynein g and the nexin link.","URL":null,"raw_pages":"e1009388","medline_journal":"PLoS Genet","ISO_journal":"PLoS Genet","authors":["Bazan R","Schrofel A","Joachimiak E","Poprzeczko M","Pigino G","Wloga D."],"DOI_URL":"https://doi.org/10.1371/journal.pgen.1009388"}},"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":50,"interactions":0,"matches":2457,"pathways":0,"proteins":2436,"proteomes":1073,"sets":0,"structural_models":{"alphafold":2103},"structures":8,"taxa":3592},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":44,"alignment:full":1872},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}