{"metadata":{"accession":"PF13739","entry_id":null,"type":"domain","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR025303","hierarchy":null,"name":{"name":"Deacetylase PdaC","short":"PdaC"},"description":[{"text":"<p>This domain forms an alpha-beta-two layer sandwich. It is found in the Bacillus subtilis proteins anti-sigma-V factor RsiV, which downregulates SigV activity [[cite:PUB00084362]], and peptidoglycan-N-acetylmuramic acid deacetylase PdaC, which catalyzes the deacetylation of N-acetylmuramic acid which makes the peptidoglycan resistant to lysosyme [[cite:PUB00084363]]. It is found in association with Heat-shock cognate 70kd protein 44kd ATPase, [pfam:PF11738].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00084363":{"PMID":22277649,"ISBN":null,"volume":"287","issue":"13","year":2012,"title":"Identification and characterization of a novel polysaccharide deacetylase C (PdaC) from Bacillus subtilis.","URL":null,"raw_pages":"9765-76","medline_journal":"J Biol Chem","ISO_journal":"J. Biol. Chem.","authors":["Kobayashi K","Sudiarta IP","Kodama T","Fukushima T","Ara K","Ozaki K","Sekiguchi J."],"DOI_URL":"http://dx.doi.org/10.1074/jbc.M111.329490"},"PUB00084362":{"PMID":16274938,"ISBN":null,"volume":"253","issue":"2","year":2005,"title":"Identification of sigma(V)-dependent genes of Bacillus subtilis.","URL":null,"raw_pages":"221-9","medline_journal":"FEMS Microbiol Lett","ISO_journal":"FEMS Microbiol. Lett.","authors":["Zellmeier S","Hofmann C","Thomas S","Wiegert T","Schumann W."],"DOI_URL":"http://dx.doi.org/10.1016/j.femsle.2005.09.056"}},"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":41,"interactions":0,"matches":3188,"pathways":0,"proteins":3167,"proteomes":2665,"sets":0,"structural_models":{"alphafold":1993},"structures":3,"taxa":3887},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":50,"alignment:full":1674},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}