{"metadata":{"accession":"PF13663","entry_id":null,"type":"domain","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR025421","hierarchy":null,"name":{"name":"Domain of unknown function (DUF4148)","short":"DUF4148"},"description":null,"wikipedia":[{"title":"Domain_of_unknown_function","extract":"<p>A <b>domain of unknown function</b> (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.</p>","thumbnail":null}],"literature":null,"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":6,"interactions":0,"matches":6113,"pathways":0,"proteins":5538,"proteomes":664,"sets":0,"structural_models":{"alphafold":3709},"structures":0,"taxa":876},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":50,"alignment:full":1986},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}