{"metadata":{"accession":"PF13387","entry_id":null,"type":"domain","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR025178","hierarchy":null,"name":{"name":"Lnb N-terminal periplasmic domain","short":"Lnb_N"},"description":[{"text":"

This domain, previously known as DUF4105, is found N-terminal in Lipoprotein N-acyltransferase Lnb from Bacteroides and related uncharacterised bacterial proteins. Lnb functions as a lipoprotein N-acyltransferase in its native cell background [[cite:PUB00158892]]. It is composed of two domains, N-terminal (this entry) and C-terminal alpha- helical transmembrane domain. The domain represented by this entry contains a highly conserved histidine residue and a well-conserved NCT motif. Its predicted structure has a significant similarity to the papain-like cysteine peptidases. In addition, the putative catalytic triad Asn-His-Cys is highly conserved. This domain is also found in combination with other domains.

","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00158892":{"PMID":39495918,"ISBN":null,"volume":"121","issue":"46","year":2024,"title":"Identification and characterization of the lipoprotein <i>N</i>-acyltransferase in <i>Bacteroides</i>.","URL":null,"raw_pages":"e2410909121","medline_journal":"Proc Natl Acad Sci U S A","ISO_journal":"Proc Natl Acad Sci U S A","authors":["Armbruster KM","Jiang J","Sartorio MG","Scott NE","Peterson JM","Sexton JZ","Feldman MF","Koropatkin NM."],"DOI_URL":"https://doi.org/10.1073/pnas.2410909121"}},"set_info":{"accession":"CL0125","name":"Peptidase_CA"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":15,"interactions":0,"matches":4839,"pathways":0,"proteins":4837,"proteomes":3704,"sets":1,"structural_models":{"alphafold":2926},"structures":0,"taxa":5476},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":61,"alignment:full":1969},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}