{"metadata":{"accession":"PF13262","entry_id":null,"type":"family","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR025127","hierarchy":null,"name":{"name":"E217 head-to-tail connector protein gp27-like","short":"E217_gp27"},"description":[{"text":"<p>This entry, previously know as DUF4054, represents Pseudomonas bacteriophage E217 head-to-tail connector protein gp27 and related proteins, including bacteriophage T1 adaptor protein gp45 [[cite:PUB00153918],[cite:PUB00163740]]. Twelve copies of the head-to-tail adaptor gp27 assemble on the portal dodecamer [[cite:PUB00153918]]. Gp27 assembles to the portal by inserting its extended C-terminal tail at the interface generated by two portal subunits, suggesting the head-to-tail connector oligomerizes upon binding instead of existing as a pre-formed ring [[cite:PUB00153918]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00153918":{"PMID":37422479,"ISBN":null,"volume":"14","issue":"1","year":2023,"title":"High-resolution cryo-EM structure of the Pseudomonas bacteriophage E217.","URL":null,"raw_pages":"4052","medline_journal":"Nat Commun","ISO_journal":"Nat Commun","authors":["Li F","Hou CD","Lokareddy RK","Yang R","Forti F","Briani F","Cingolani G."],"DOI_URL":"https://doi.org/10.1038/s41467-023-39756-z"},"PUB00163740":{"PMID":40143278,"ISBN":null,"volume":"17","issue":"3","year":2025,"title":"The In Situ Structure of T-Series T1 Reveals a Conserved Lambda-Like Tail Tip.","URL":null,"raw_pages":"351","medline_journal":"Viruses","ISO_journal":"Viruses","authors":["Chen Y","Xiao H","Zhou J","Peng Z","Peng Y","Song J","Zheng J","Liu H."],"DOI_URL":"https://doi.org/10.3390/v17030351"}},"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":3,"interactions":0,"matches":947,"pathways":0,"proteins":946,"proteomes":868,"sets":0,"structural_models":{"alphafold":371},"structures":8,"taxa":1880},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":21,"alignment:full":438},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}