This presumed domain is functionally uncharacterised. This domain family is found in bacteria, and is typically between 310 and 324 amino acids in length. According to structure prediction and comparison (DALI server) it is suggested that it may adopt a metallo-dependent phosphatase fold.
","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"A domain of unknown function (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.
","thumbnail":null}],"literature":null,"set_info":{"accession":"CL0163","name":"Calcineurin"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":2,"interactions":0,"matches":10,"pathways":0,"proteins":10,"proteomes":5,"sets":1,"structural_models":{"alphafold":10},"structures":0,"taxa":18},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":2,"alignment:full":10},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}