{"metadata":{"accession":"PF13225","entry_id":null,"type":"domain","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR025114","hierarchy":null,"name":{"name":"Beta-carotene isomerase D27-like, C-terminal","short":"D27-like_C"},"description":[{"text":"<p>This is the C-terminal domain of Beta-carotene isomerase D27 that may contain an iron binding domain [[cite:PUB00095646]]. Beta-carotene isomerase D27 (also known as Protein DWARF-27) from plants is involved in strigolactones biosynthesis. It is a beta-carotene isomerase that converts all-trans-beta-carotene into 9-cis-beta-carotene, which is cleaved by CCD7 into a 9-cis-configured aldehyde [[cite:PUB00088582],[cite:PUB00095645]]. This is an iron-containing protein that localises in chloroplasts and is expressed mainly in vascular cells of shoots and roots [[cite:PUB00095646]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00095646":{"PMID":19470589,"ISBN":null,"volume":"21","issue":"5","year":2009,"title":"DWARF27, an iron-containing protein required for the biosynthesis of strigolactones, regulates rice tiller bud outgrowth.","URL":null,"raw_pages":"1512-25","medline_journal":"Plant Cell","ISO_journal":"Plant Cell","authors":["Lin H","Wang R","Qian Q","Yan M","Meng X","Fu Z","Yan C","Jiang B","Su Z","Li J","Wang Y."],"DOI_URL":null},"PUB00088582":{"PMID":22422982,"ISBN":null,"volume":"335","issue":"6074","year":2012,"title":"The path from β-carotene to carlactone, a strigolactone-like plant hormone.","URL":null,"raw_pages":"1348-51","medline_journal":"Science","ISO_journal":"Science","authors":["Alder A","Jamil M","Marzorati M","Bruno M","Vermathen M","Bigler P","Ghisla S","Bouwmeester H","Beyer P","Al-Babili S."],"DOI_URL":"https://doi.org/10.1126/science.1218094"},"PUB00095645":{"PMID":22623516,"ISBN":null,"volume":"159","issue":"3","year":2012,"title":"The Arabidopsis ortholog of rice DWARF27 acts upstream of MAX1 in the control of plant development by strigolactones.","URL":null,"raw_pages":"1073-85","medline_journal":"Plant Physiol","ISO_journal":"Plant Physiol","authors":["Waters MT","Brewer PB","Bussell JD","Smith SM","Beveridge CA."],"DOI_URL":null}},"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":46,"interactions":0,"matches":1918,"pathways":0,"proteins":1910,"proteomes":516,"sets":0,"structural_models":{"alphafold":1559},"structures":0,"taxa":1511},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":33,"alignment:full":1248},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}