{"metadata":{"accession":"PF13186","entry_id":null,"type":"domain","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR023885","hierarchy":null,"name":{"name":"Iron-sulfur cluster-binding domain","short":"SPASM"},"description":[{"text":"<p>This domain occurs as an additional C-terminal iron-sulfur cluster binding domain in many radical SAM domain, [pfam:PF04055] proteins. The domain occurs in a number of proteins that modify a protein to become an active enzyme, or a peptide to become a ribosomal natural product. The domain is named SPASM because it occurs in the maturases of Subilitosin, PQQ, Anaerobic Sulfatases, and Mycofactocin.</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00055953":{"PMID":21478363,"ISBN":null,"volume":"193","issue":"11","year":2011,"title":"Biological systems discovery in silico: radical S-adenosylmethionine protein families and their target peptides for posttranslational modification.","URL":null,"raw_pages":"2745-55","medline_journal":"J Bacteriol","ISO_journal":"J. Bacteriol.","authors":["Haft DH","Basu MK."],"DOI_URL":"http://dx.doi.org/10.1128/JB.00040-11"}},"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":93,"interactions":0,"matches":16683,"pathways":0,"proteins":16680,"proteomes":9267,"sets":0,"structural_models":{"alphafold":11292},"structures":10,"taxa":14353},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":136,"alignment:full":9067},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}