Based on Eubacterium rectale gene EUBREC_3695. As seen in gene expression experiments (http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE14737), it appears to be upregulated in the presence of Bacteroides thetaiotaomicron vs when isolated in culture [[cite:PUB00056060]].
","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"A domain of unknown function (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.
","thumbnail":null}],"literature":{"PUB00056060":{"PMID":19321416,"ISBN":null,"volume":"106","issue":"14","year":2009,"title":"Characterizing a model human gut microbiota composed of members of its two dominant bacterial phyla.","URL":null,"raw_pages":"5859-64","medline_journal":"Proc Natl Acad Sci U S A","ISO_journal":"Proc. Natl. Acad. Sci. U.S.A.","authors":["Mahowald MA","Rey FE","Seedorf H","Turnbaugh PJ","Fulton RS","Wollam A","Shah N","Wang C","Magrini V","Wilson RK","Cantarel BL","Coutinho PM","Henrissat B","Crock LW","Russell A","Verberkmoes NC","Hettich RL","Gordon JI."],"DOI_URL":"http://dx.doi.org/10.1073/pnas.0901529106"}},"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":4,"interactions":0,"matches":266,"pathways":0,"proteins":264,"proteomes":261,"sets":0,"structural_models":{"alphafold":175},"structures":0,"taxa":479},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":17,"alignment:full":237},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}