{"metadata":{"accession":"PF12941","entry_id":null,"type":"family","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR024350","hierarchy":null,"name":{"name":"HCV NS5a protein C-terminal region","short":"HCV_NS5a_C"},"description":[{"text":"<p>This is a family of proteins found in the hepatitis C virus. This family contains the C-terminal region of the NS5A protein. CC The molecular function of the non-structural 5a protein is uncertain.  The NS5a protein is phosphorylated when expressed in mammalian cells.  It is thought to interact with the ds RNA dependent (interferon inducible) kinase PKR, [swissprot:P19525].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"NS5_(HCV)","extract":"<p><b>NS5</b> may refer to:</p>","thumbnail":null}],"literature":null,"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":27,"interactions":0,"matches":2488,"pathways":0,"proteins":2466,"proteomes":13,"sets":0,"structural_models":{"alphafold":25},"structures":1,"taxa":165},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":1,"alignment:full":1},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":{"accession":"4j1v","name":"Functional and structural studies of MOBKL1B, a Salvador/Warts/Hippo tumor suppressor pathway, in HCV replication"}}}