{"metadata":{"accession":"PF12843","entry_id":null,"type":"family","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR024530","hierarchy":null,"name":{"name":"Putative quorum-sensing-regulated virulence factor","short":"QSregVF_b"},"description":[{"text":"<p>QSregVF_b is a family of short Pseudomonas proteins that are potential virulence factors. The structure of UniProtKB:Q9HY15 a secreted protein has been solved and deposited as PDB:3npd, from [pfam:PF13652]. It is predicted that these two adjacent proteins form a single transcriptional unit based on the prediction that together they interact with their adjacent protein PotD, which is the putrescine-binding periplasmic protein in the polyamine uptake system comprising PotABCD. These two adjacent proteins are predicted to be quroum-sensing-regulated virulence factors [[cite:PUB00075641]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00075641":{"PMID":24174223,"ISBN":null,"volume":"82","issue":"6","year":2014,"title":"Crystal structure of a putative quorum sensing-regulated protein (PA3611) from the Pseudomonas-specific DUF4146 family.","URL":null,"raw_pages":"1086-92","medline_journal":"Proteins","ISO_journal":"Proteins","authors":["Das D","Chiu HJ","Farr CL","Grant JC","Jaroszewski L","Knuth MW","Miller MD","Tien HJ","Elsliger MA","Deacon AM","Godzik A","Lesley SA","Wilson IA."],"DOI_URL":"http://dx.doi.org/10.1002/prot.24455"}},"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":12,"interactions":0,"matches":4734,"pathways":0,"proteins":4730,"proteomes":4578,"sets":0,"structural_models":{"alphafold":3005},"structures":0,"taxa":6351},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":70,"alignment:full":1891},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}