{"metadata":{"accession":"PF12822","entry_id":null,"type":"family","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR024529","hierarchy":null,"name":{"name":"ECF transporter, substrate-specific component","short":"ECF_trnsprt"},"description":[{"text":"<p>Energy-coupling factor (ECF) transporters consist of a substrate-specific component (known as the S component),  and an energy-coupling module [[cite:PUB00056162]]. The substrate-binding  component is a small integral membrane protein which  captures specific substrates and forms an active transporter  in the presence of the energy-coupling AT module.</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00057473":{"PMID":21890906,"ISBN":null,"volume":"39","issue":"22","year":2011,"title":"Evolution of the deaminase fold and multiple origins of eukaryotic editing and mutagenic nucleic acid deaminases from bacterial toxin systems.","URL":null,"raw_pages":"9473-97","medline_journal":"Nucleic Acids Res","ISO_journal":"Nucleic Acids Res.","authors":["Iyer LM","Zhang D","Rogozin IB","Aravind L."],"DOI_URL":"http://dx.doi.org/10.1093/nar/gkr691"},"PUB00056162":{"PMID":18931129,"ISBN":null,"volume":"191","issue":"1","year":2009,"title":"A novel class of modular transporters for vitamins in prokaryotes.","URL":null,"raw_pages":"42-51","medline_journal":"J Bacteriol","ISO_journal":"J. Bacteriol.","authors":["Rodionov DA","Hebbeln P","Eudes A","ter Beek J","Rodionova IA","Erkens GB","Slotboom DJ","Gelfand MS","Osterman AL","Hanson AD","Eitinger T."],"DOI_URL":"http://dx.doi.org/10.1128/JB.01208-08"}},"set_info":{"accession":"CL0315","name":"Gx_transp"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":9,"interactions":0,"matches":8472,"pathways":0,"proteins":8451,"proteomes":3797,"sets":1,"structural_models":{"alphafold":5684},"structures":17,"taxa":5807},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":40,"alignment:full":4783},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}