{"metadata":{"accession":"PF12673","entry_id":null,"type":"domain","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR024300","hierarchy":null,"name":{"name":"SipL, SPOCS domain","short":"SipL"},"description":[{"text":"<p>This is the SPOCS domain found in three copies in SipL from C. difficile, N-terminal to the LysM domain ([pfam:PF01476]) [[cite:PUB00101296]]. SipL (for SpoIVA-interacting protein) is involved in coat localization, and, together with SpoIVA, is a critical spore morphogenetic protein [[cite:PUB00101297]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00101296":{"PMID":35065768,"ISBN":null,"volume":"57","issue":"3","year":2022,"title":"Bacterial developmental checkpoint that directly monitors cell surface morphogenesis.","URL":null,"raw_pages":"344-360.e6","medline_journal":"Dev Cell","ISO_journal":"Dev Cell","authors":["Delerue T","Anantharaman V","Gilmore MC","Popham DL","Cava F","Aravind L","Ramamurthi KS."],"DOI_URL":null},"PUB00101297":{"PMID":23292781,"ISBN":null,"volume":"195","issue":"6","year":2013,"title":"SpoIVA and SipL are Clostridium difficile spore morphogenetic proteins.","URL":null,"raw_pages":"1214-25","medline_journal":"J Bacteriol","ISO_journal":"J Bacteriol","authors":["Putnam EE","Nock AM","Lawley TD","Shen A."],"DOI_URL":null}},"set_info":{"accession":"CL0731","name":"SPOCS"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":27,"interactions":0,"matches":2472,"pathways":0,"proteins":1154,"proteomes":757,"sets":1,"structural_models":{"alphafold":782},"structures":0,"taxa":1335},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":150,"alignment:full":1787},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}