{"metadata":{"accession":"PF12603","entry_id":null,"type":"domain","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR022531","hierarchy":null,"name":{"name":"RNA-directed RNA polymerase L, PA-C-like domain","short":"L_PA-C-like"},"description":[{"text":"<p>This domain is found in RNA-directed RNA polymerase L from from Bunyavirales. It has been described as the PA-C-like domain which forms a narrow and positively charged cleft with the thumb domain, where the 3' RNA is likely bound [[cite:PUB00101134]]. It is found in association with [pfam:PF04196].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00101134":{"PMID":32313945,"ISBN":null,"volume":"48","issue":"10","year":2020,"title":"Structural and functional characterization of the severe fever with thrombocytopenia syndrome virus L protein.","URL":null,"raw_pages":"5749-5765","medline_journal":"Nucleic Acids Res","ISO_journal":"Nucleic Acids Res","authors":["Vogel D","Thorkelsson SR","Quemin ERJ","Meier K","Kouba T","Gogrefe N","Busch C","Reindl S","Gunther S","Cusack S","Grunewald K","Rosenthal M."],"DOI_URL":null}},"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":6,"interactions":0,"matches":432,"pathways":0,"proteins":432,"proteomes":131,"sets":0,"structural_models":{"alphafold":123},"structures":13,"taxa":363},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":53,"alignment:full":76},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}