{"metadata":{"accession":"PF12562","entry_id":null,"type":"domain","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR022219","hierarchy":null,"name":{"name":"Poxvirus telomere-binding protein I6, C-terminal domain","short":"Pox_I6_C"},"description":[{"text":"<p>This domain is found at the C-terminal end of Telomere-binding protein I6 from poxvirus, I6 binds tightly and with great specificity to the hairpin form of the viral telomeric sequence. This protein is thought to play a role in the initiation of vaccinia virus genome replication and/or genome encapsidation [[cite:PUB00010106]]. The family is found in association with [pfam:PF04595].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00010106":{"PMID":11581377,"ISBN":null,"volume":"75","issue":"21","year":2001,"title":"Vaccinia virus telomeres: interaction with the viral I1, I6, and K4 proteins.","URL":null,"raw_pages":"10090-105","medline_journal":"J Virol","ISO_journal":"J. Virol.","authors":["DeMasi J","Du S","Lennon D","Traktman P."],"DOI_URL":"http://dx.doi.org/10.1128/JVI.75.21.10090-10105.2001"}},"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":1,"interactions":0,"matches":112,"pathways":0,"proteins":112,"proteomes":33,"sets":0,"structural_models":{"alphafold":0,"bfvd":1},"structures":0,"taxa":121},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":6,"alignment:full":27},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}