{"metadata":{"accession":"PF12478","entry_id":null,"type":"family","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR022166","hierarchy":null,"name":{"name":"UBAP2/protein lingerer","short":"UBAP2-Lig"},"description":[{"text":"<p>This entry includes ubiquitin-associated protein 2 (UBAP2) from humans and protein lingerer (lig) from Drosophila melanogaster. Lig  is a cytoplasmic protein involved in initiation and termination of copulation [[cite:PUB00092497]]. Lig can act as a growth suppressor that associates with the RNA-binding proteins Fragile X messenger ribonucleoprotein 1 (FMR1) and Caprin (Capr) and directly interacts with and regulates the RNA-binding protein Rasputin (Rin) [[cite:PUB00069369]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00092497":{"PMID":12524348,"ISBN":null,"volume":"162","issue":"4","year":2002,"title":"lingerer, a Drosophila gene involved in initiation and termination of copulation, encodes a set of novel cytoplasmic proteins.","URL":null,"raw_pages":"1775-89","medline_journal":"Genetics","ISO_journal":"Genetics","authors":["Kuniyoshi H","Baba K","Ueda R","Kondo S","Awano W","Juni N","Yamamoto D."],"DOI_URL":null},"PUB00069369":{"PMID":23874212,"ISBN":null,"volume":"9","issue":"7","year":2013,"title":"The RNA-binding proteins FMR1, rasputin and caprin act together with the UBA protein lingerer to restrict tissue growth in Drosophila melanogaster.","URL":null,"raw_pages":"e1003598","medline_journal":"PLoS Genet","ISO_journal":"PLoS Genet.","authors":["Baumgartner R","Stocker H","Hafen E."],"DOI_URL":"http://dx.doi.org/10.1371/journal.pgen.1003598"}},"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":23,"interactions":0,"matches":4782,"pathways":0,"proteins":4781,"proteomes":1032,"sets":0,"structural_models":{"alphafold":3803},"structures":0,"taxa":3518},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":13,"alignment:full":3560},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}