This entry represents a domain from a family of uncharacterised proteins found predominantly in Bacilli. The domain is approximately 120 amino acids in length. Proteins containing this domain are primarily found in the order Bacillales, including genera such as Bacillus, Brevibacillus, and Thermoactinomyces. The domain contains predicted transmembrane regions.
","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"A domain of unknown function (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.
","thumbnail":null}],"literature":null,"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":2,"interactions":0,"matches":551,"pathways":0,"proteins":547,"proteomes":547,"sets":0,"structural_models":{"alphafold":327},"structures":0,"taxa":700},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":91,"alignment:full":258},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}