{"metadata":{"accession":"PF12331","entry_id":null,"type":"repeat","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR022093","hierarchy":null,"name":{"name":"Rad26-like, helical repeats","short":"Rad26-like_helical_rpts"},"description":[{"text":"<p>This domain is found in Rad26 from Myceliophthora thermophila ([swissprot:G2QDY6]) and similar fungal proteins. Rad26 is a functional subunit of the Rad3-Rad26 complex that is responsible for bringing the kinase to sites of DNA damage. The central region of Rad26 is formed by five helical repeats forming an alpha-solenoid arrangement [[cite:PUB00100970]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00100970":{"PMID":28314775,"ISBN":null,"volume":"292","issue":"20","year":2017,"title":"Insights into Rad3 kinase recruitment from the crystal structure of the DNA damage checkpoint protein Rad26.","URL":null,"raw_pages":"8149-8157","medline_journal":"J Biol Chem","ISO_journal":"J Biol Chem","authors":["Andersen KR."],"DOI_URL":null}},"set_info":{"accession":"CL0020","name":"TPR"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":16,"interactions":0,"matches":896,"pathways":0,"proteins":886,"proteomes":870,"sets":1,"structural_models":{"alphafold":727},"structures":1,"taxa":1710},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":37,"alignment:full":698},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}