{"metadata":{"accession":"PF12059","entry_id":null,"type":"family","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR021927","hierarchy":null,"name":{"name":"Protein of unknown function (DUF3540)","short":"DUF3540"},"description":[{"text":"<p>This family of proteins is functionally uncharacterised. This protein is found in bacteria. Proteins in this family are typically between 212 to 238 amino acids in length. This protein has a conserved SCL sequence motif.</p>","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"<p>A <b>domain of unknown function</b> (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.</p>","thumbnail":null}],"literature":{"PUB00105085":{"PMID":17660433,"ISBN":null,"volume":"153","issue":"Pt 8","year":2007,"title":"In vivo expression technology identifies a type VI secretion system locus in Burkholderia pseudomallei that is induced upon invasion of macrophages.","URL":null,"raw_pages":"2689-2699","medline_journal":"Microbiology (Reading)","ISO_journal":"Microbiology (Reading)","authors":["Shalom G","Shaw JG","Thomas MS."],"DOI_URL":null}},"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":3,"interactions":0,"matches":608,"pathways":0,"proteins":563,"proteomes":404,"sets":0,"structural_models":{"alphafold":356},"structures":0,"taxa":762},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":13,"alignment:full":253},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}