{"metadata":{"accession":"PF11998","entry_id":null,"type":"family","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR021883","hierarchy":null,"name":{"name":"Low psii accumulation1 / Rep27","short":"DUF3493"},"description":[{"text":"<p>This family includes members such as low psii accumulation1 (lpa1) from plants as well as Rep27 proteins found in unicellular green alga Chlamydomonas reinhardtii. The Arabidopsis LPA1 is a chaperone required for efficient photosystem II (PSII) assembly. It binds to psbA during de novo biogenesis of PSII [[cite:PUB00086019]]. Other studies show that REP27 in Chlamydomonas reinhardtii chloroplast thylakoids, plays a dual role in the regulation of D1 protein turnover by facilitating cotranslational biosynthesis insertion (C-terminal domain) and activation (tetratricopeptide repeat [TPR] motifs) of the nascent D1 during the PSII repair process [[cite:PUB00138194]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00138194":{"PMID":19574473,"ISBN":null,"volume":"151","issue":"1","year":2009,"title":"Mechanism of REP27 protein action in the D1 protein turnover and photosystem II repair from photodamage.","URL":null,"raw_pages":"88-99","medline_journal":"Plant Physiol","ISO_journal":"Plant Physiol","authors":["Dewez D","Park S","Garcia-Cerdan JG","Lindberg P","Melis A."],"DOI_URL":null},"PUB00086019":{"PMID":16531500,"ISBN":null,"volume":"18","issue":"4","year":2006,"title":"LOW PSII ACCUMULATION1 is involved in efficient assembly of photosystem II in Arabidopsis thaliana.","URL":null,"raw_pages":"955-69","medline_journal":"Plant Cell","ISO_journal":"Plant Cell","authors":["Peng L","Ma J","Chi W","Guo J","Zhu S","Lu Q","Lu C","Zhang L."],"DOI_URL":"https://doi.org/10.1105/tpc.105.037689"}},"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":38,"interactions":0,"matches":1514,"pathways":0,"proteins":1512,"proteomes":698,"sets":0,"structural_models":{"alphafold":1181},"structures":0,"taxa":1944},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":58,"alignment:full":1008},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}