{"metadata":{"accession":"PF11968","entry_id":null,"type":"family","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR021867","hierarchy":null,"name":{"name":"25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2","short":"Bmt2"},"description":[{"text":"<p>This entry represents Bmt2 and its homogues. In Saccharomyces cerevisiae, Bmt2 is a nucleolar S-adenosylmethionine-dependent rRNA  methyltransferase that is responsible for the N-1-methyl-adenosine base modification of  25S rRNA [[cite:PUB00066965]].It specifically methylates the N1  position of adenine 2142 in 25S rRNA [[cite:PUB00066965]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00066965":{"PMID":23558746,"ISBN":null,"volume":null,"issue":null,"year":2013,"title":"Identification of a novel methyltransferase, Bmt2, responsible for the N-1-methyl-adenosine base modification of 25S rRNA in Saccharomyces cerevisiae.","URL":null,"raw_pages":null,"medline_journal":"Nucleic Acids Res","ISO_journal":"Nucleic Acids Res.","authors":["Sharma S","Watzinger P","Kotter P","Entian KD."],"DOI_URL":null}},"set_info":{"accession":"CL0063","name":"NADP_Rossmann"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":40,"interactions":0,"matches":2466,"pathways":0,"proteins":2402,"proteomes":2182,"sets":1,"structural_models":{"alphafold":2062},"structures":8,"taxa":5584},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":24,"alignment:full":1958},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}