{"metadata":{"accession":"PF11934","entry_id":null,"type":"family","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR024599","hierarchy":null,"name":{"name":"Domain of unknown function (DUF3452)","short":"DUF3452"},"description":[{"text":"<p>This presumed domain is functionally uncharacterised. This domain is found in eukaryotes. This domain is typically between 124 to 150 amino acids in length. This domain is found associated with [pfam:PF01858], [pfam:PF01857]. This domain has a single completely conserved residue W that may be functionally important.</p>","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"<p>A <b>domain of unknown function</b> (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.</p>","thumbnail":null}],"literature":null,"set_info":{"accession":"CL0065","name":"Cyclin"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":53,"interactions":0,"matches":5123,"pathways":0,"proteins":5112,"proteomes":1687,"sets":1,"structural_models":{"alphafold":4435},"structures":2,"taxa":5318},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":37,"alignment:full":3877},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}