This is a family of beta-barrel porin-like outer membrane proteins from enteropathogenic Gram-negative bacteria. Intimins and invasins are virulence factors produced by pathogenic Gram-negative bacteria. They carry C-terminal extracellular passenger domains that are involved in adhesion to host cells and N-terminal beta domains that are embedded in the outer membrane. This family represents the beta-barrel porin-like domain in the outer membrane that can be found in intimins, invasins and some inverse autotransporters [[cite:PUB00059501],[cite:PUB00081211]].
","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Intimin","extract":"Intimin is a virulence factor (adhesin) of EPEC and EHEC E. coli strains. It is an attaching and effacing (A/E) protein, which with other virulence factors is necessary and responsible for enteropathogenic and enterohaemorrhagic diarrhoea.
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"}],"literature":{"PUB00059501":{"PMID":22658748,"ISBN":null,"volume":null,"issue":null,"year":2012,"title":"Crystal 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