{"metadata":{"accession":"PF11917","entry_id":null,"type":"family","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR021842","hierarchy":null,"name":{"name":"Protein of unknown function (DUF3435)","short":"DUF3435"},"description":[{"text":"<p>This family of proteins are functionally uncharacterised. This protein is found in eukaryotes. Proteins in this family are typically between 435 to 791 amino acids in length. This family is related to [pfam:PF00589] suggesting it may be an integrase enzyme.</p>","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"<p>A <b>domain of unknown function</b> (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.</p>","thumbnail":null}],"literature":null,"set_info":{"accession":"CL0382","name":"DNA-mend"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":95,"interactions":0,"matches":3997,"pathways":0,"proteins":3722,"proteomes":736,"sets":1,"structural_models":{"alphafold":3105},"structures":0,"taxa":1583},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":19,"alignment:full":3654},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}