{"metadata":{"accession":"PF11895","entry_id":null,"type":"family","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR024589","hierarchy":null,"name":{"name":"Fungal peroxidase extension region","short":"Peroxidase_ext"},"description":[{"text":"<p>This region is found as an extension to a haem peroxidase domain in some fungi. This region is about 80 amino acids in length and forms an extended structure on the surface of the peroxidase domain [pfam:PF00141].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Haem_peroxidase","extract":"<p><b>Haem peroxidases</b> (or <b>heme peroxidases</b>) are haem-containing enzymes that use hydrogen peroxide as the electron acceptor to catalyse a number of oxidative reactions. Most haem peroxidases follow the reaction scheme:</p><dl><dd>Fe<sup>3+</sup> + H<sub>2</sub>O<sub>2</sub> <span class=\"mwe-math-element mwe-math-element-inline\"><img src=\"https://wikimedia.org/api/rest_v1/media/math/render/svg/1c37b981df851b9e54e489e017b1481e37d418f3\" class=\"mwe-math-fallback-image-inline mw-invert skin-invert\" aria-hidden=\"true\" style=\"vertical-align:-0.338ex;width:2.324ex;height:1.843ex\" /></span> [Fe<sup>4+</sup>=O]R' (Compound I) + H<sub>2</sub>O</dd></dl><dl><dd>[Fe<sup>4+</sup>=O]R' + substrate → [Fe<sup>4+</sup>=O]R (Compound II) + oxidized substrate</dd></dl><dl><dd>[Fe<sup>4+</sup>=O]R + substrate → Fe<sup>3+</sup> + H<sub>2</sub>O + oxidized substrate</dd></dl>","thumbnail":null}],"literature":null,"set_info":{"accession":"CL0617","name":"Peroxidase"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":28,"interactions":0,"matches":1408,"pathways":0,"proteins":1401,"proteomes":169,"sets":1,"structural_models":{"alphafold":1209},"structures":76,"taxa":497},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":25,"alignment:full":1093},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}