{"metadata":{"accession":"PF11871","entry_id":null,"type":"domain","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR021812","hierarchy":null,"name":{"name":"Domain of unknown function (DUF3391)","short":"DUF3391"},"description":[{"text":"<p>This functionally uncharacterised, N-terminal domain is found in a number of bacterial proteins, including Cyclic di-GMP phosphodiesterase PA4108 ([swissprot:Q9HWS0]). It is often found associated with the HD domain [pfam:PF13328].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"<p>A <b>domain of unknown function</b> (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.</p>","thumbnail":null}],"literature":null,"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":10,"interactions":0,"matches":3829,"pathways":0,"proteins":3829,"proteomes":2061,"sets":0,"structural_models":{"alphafold":2268},"structures":0,"taxa":2946},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":128,"alignment:full":1775},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}