{"metadata":{"accession":"PF11841","entry_id":null,"type":"repeat","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR024574","hierarchy":null,"name":{"name":"ELMO, armadillo-like helical domain","short":"ELMO_ARM"},"description":[{"text":"<p>This domain is found in eukaryotes and predominantly in ELMO (Elongation and Cell motility) proteins and corresponds to the armadillo repeats domain (ARR). It may play an important role in defining the functions of the ELMO family members and may be functionally linked to the ELMO domain in these proteins [[cite:PUB00073882],[cite:PUB00109603]], being involved in protein-protein interactions.</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00109603":{"PMID":30604775,"ISBN":null,"volume":"10","issue":"1","year":2019,"title":"Structure of BAI1/ELMO2 complex reveals an action mechanism of adhesion GPCRs via ELMO family scaffolds.","URL":null,"raw_pages":"51","medline_journal":"Nat Commun","ISO_journal":"Nat Commun","authors":["Weng Z","Situ C","Lin L","Wu Z","Zhu J","Zhang R."],"DOI_URL":null},"PUB00073882":{"PMID":23014990,"ISBN":null,"volume":"287","issue":"47","year":2012,"title":"ELMO domains, evolutionary and functional characterization of a novel GTPase-activating protein (GAP) domain for Arf protein family GTPases.","URL":null,"raw_pages":"39538-53","medline_journal":"J Biol Chem","ISO_journal":"J. Biol. Chem.","authors":["East MP","Bowzard JB","Dacks JB","Kahn RA."],"DOI_URL":"http://dx.doi.org/10.1074/jbc.M112.417477"}},"set_info":{"accession":"CL0020","name":"TPR"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":83,"interactions":0,"matches":5951,"pathways":0,"proteins":5922,"proteomes":2423,"sets":1,"structural_models":{"alphafold":5286},"structures":15,"taxa":6579},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":31,"alignment:full":4845},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}