Alternative complex III (ACIII) is a multisubunit quinol:electron acceptor oxidoreductase that couples quinol oxidation with transmembrane proton translocation similar to bc1 complex (or complex III). It is a key component of the respiratory and photosynthetic electron transport chains in many bacteria. It has six subunits (ActA-F), ActD subunit represented in this entry. The transmembrane regions of this subunit form part of the TM arm of the complex [[cite:PUB00099731],[cite:PUB00099732]]. Although the function of this subunit is not clear, it may play a role in stabilizing the TM region of ACIII which contributes to a stable menaquinol binding pocket and proton translocation passage [[cite:PUB00099732]].
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