{"metadata":{"accession":"PF11808","entry_id":null,"type":"family","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR021766","hierarchy":null,"name":{"name":"Phosphate regulon sensor protein PhoR","short":"PhoR"},"description":[{"text":"<p>This family is only found in bacteria. Family members include PhoR. A member of the two-component regulatory system PhoR/PhoB involved in the phosphate regulon genes expression. PhoR is the bifunctional histidine autokinase/phospho-PhoB phosphatase that donates a phosphoryl group to PhoB when environmental Pi is limiting and removes the phosphoryl group from phosphorylated PhoB (PhoB-P) when environmental Pi is abundant [[cite:PUB00076908]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00076908":{"PMID":24563032,"ISBN":null,"volume":"196","issue":"9","year":2014,"title":"The PhoU protein from Escherichia coli interacts with PhoR, PstB, and metals to form a phosphate-signaling complex at the membrane.","URL":null,"raw_pages":"1741-52","medline_journal":"J Bacteriol","ISO_journal":"J. Bacteriol.","authors":["Gardner SG","Johns KD","Tanner R","McCleary WR."],"DOI_URL":"http://dx.doi.org/10.1128/JB.00029-14"}},"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":13,"interactions":0,"matches":3648,"pathways":0,"proteins":3648,"proteomes":3614,"sets":0,"structural_models":{"alphafold":2271},"structures":0,"taxa":4812},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":59,"alignment:full":1413},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}