{"metadata":{"accession":"PF11776","entry_id":null,"type":"family","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR024572","hierarchy":null,"name":{"name":"Nickel/cobalt transporter regulator","short":"RcnB"},"description":[{"text":"<p>RcnB is a family of Proteobacteria proteins. RcnB is required for maintaining metal ion homeostasis, in conjunction with the efflux pump RcnA, family NicO, [pfam:PF03824] [[cite:PUB00075667]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00075669":{"PMID":21665978,"ISBN":null,"volume":"193","issue":"15","year":2011,"title":"RcnB is a periplasmic protein essential for maintaining intracellular Ni and Co concentrations in Escherichia coli.","URL":null,"raw_pages":"3785-93","medline_journal":"J Bacteriol","ISO_journal":"J. Bacteriol.","authors":["Bleriot C","Effantin G","Lagarde F","Mandrand-Berthelot MA","Rodrigue A."],"DOI_URL":"http://dx.doi.org/10.1128/JB.05032-11"},"PUB00075667":{"PMID":15805538,"ISBN":null,"volume":"187","issue":"8","year":2005,"title":"Identification of rcnA (yohM), a nickel and cobalt resistance gene in Escherichia coli.","URL":null,"raw_pages":"2912-6","medline_journal":"J Bacteriol","ISO_journal":"J. Bacteriol.","authors":["Rodrigue A","Effantin G","Mandrand-Berthelot MA."],"DOI_URL":"http://dx.doi.org/10.1128/JB.187.8.2912-2916.2005"},"PUB00035608":{"PMID":16956381,"ISBN":null,"volume":"62","issue":"1","year":2006,"title":"Nickel homeostasis in Escherichia coli - the rcnR-rcnA efflux pathway and its linkage to NikR function.","URL":null,"raw_pages":"252-62","medline_journal":"Mol Microbiol","ISO_journal":"Mol. Microbiol.","authors":["Iwig JS","Rowe JL","Chivers PT."],"DOI_URL":"http://dx.doi.org/10.1111/j.1365-2958.2006.05369.x"}},"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":9,"interactions":0,"matches":3946,"pathways":0,"proteins":3944,"proteomes":2448,"sets":0,"structural_models":{"alphafold":2403},"structures":1,"taxa":3185},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":50,"alignment:full":1712},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}