{"metadata":{"accession":"PF11658","entry_id":null,"type":"domain","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR063479","hierarchy":null,"name":{"name":"Cellulose biosynthesis protein BcsG C-terminal domain","short":"CBP_BcsG"},"description":[{"text":"<p>CBP_BcsG is a component of bacterial cellulose synthase complex that plays a role in biofilm formation in bacteria [[cite:PUB00075887]]. It is a Zn(2+)-dependent phosphoethanolamine transferase that catalyses transfer of phosphoethanolamine residues from membrane phosphatidylethanolamine to the glucosyl residues in the nascent cellulose chain [[cite:PUB00100650],[cite:PUB00100651],[cite:PUB00100652],[cite:PUB00100653]]. This entry represents the C-terminal domain which functions as a phosphoethanolamine transferase [[cite:PUB00100653]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00100651":{"PMID":29348224,"ISBN":null,"volume":"359","issue":"6373","year":2018,"title":"A bacterial coat that is not pure cotton.","URL":null,"raw_pages":"276-277","medline_journal":"Science","ISO_journal":"Science","authors":["Galperin MY","Shalaeva DN."],"DOI_URL":null},"PUB00100650":{"PMID":29348238,"ISBN":null,"volume":"359","issue":"6373","year":2018,"title":"Phosphoethanolamine cellulose: A naturally produced chemically modified cellulose.","URL":null,"raw_pages":"334-338","medline_journal":"Science","ISO_journal":"Science","authors":["Thongsomboon W","Serra DO","Possling A","Hadjineophytou C","Hengge R","Cegelski L."],"DOI_URL":null},"PUB00075887":{"PMID":26077867,"ISBN":null,"volume":null,"issue":null,"year":2015,"title":"Bacterial cellulose biosynthesis: diversity of operons, subunits, products, and functions.","URL":null,"raw_pages":null,"medline_journal":"Trends Microbiol","ISO_journal":"Trends Microbiol.","authors":["Romling U","Galperin MY."],"DOI_URL":"http://dx.doi.org/10.1016/j.tim.2015.05.005"},"PUB00100653":{"PMID":32152228,"ISBN":null,"volume":"295","issue":"18","year":2020,"title":"The <i>Escherichia coli</i> cellulose synthase subunit G (BcsG) is a Zn<sup>2+</sup>-dependent phosphoethanolamine transferase.","URL":null,"raw_pages":"6225-6235","medline_journal":"J Biol Chem","ISO_journal":"J Biol Chem","authors":["Anderson AC","Burnett AJN","Hiscock L","Maly KE","Weadge JT."],"DOI_URL":null},"PUB00100652":{"PMID":30017920,"ISBN":null,"volume":"430","issue":"18 Pt B","year":2018,"title":"Structural and Functional Characterization of the BcsG Subunit of the Cellulose Synthase in Salmonella typhimurium.","URL":null,"raw_pages":"3170-3189","medline_journal":"J Mol Biol","ISO_journal":"J Mol Biol","authors":["Sun L","Vella P","Schnell R","Polyakova A","Bourenkov G","Li F","Cimdins A","Schneider TR","Lindqvist Y","Galperin MY","Schneider G","Romling U."],"DOI_URL":null}},"set_info":{"accession":"CL0088","name":"Alk_phosphatase"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":3,"interactions":0,"matches":721,"pathways":0,"proteins":719,"proteomes":701,"sets":1,"structural_models":{"alphafold":416},"structures":9,"taxa":1030},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":17,"alignment:full":209},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":{"accession":"5olt","name":"Crystal structure of the extramembrane domain of the cellulose biosynthetic protein BcsG from Salmonella typhimurium"}}}