{"metadata":{"accession":"PF11586","entry_id":null,"type":"family","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR021636","hierarchy":null,"name":{"name":"Protein of unknown function (DUF3242)","short":"DUF3242"},"description":[{"text":"<p>This protein from Thermotoga maritima is a hypothetical ORFan protein, TM1622, whose structure has been determined. The protein is composed of seven beta strands and three alpha helices [[cite:PUB00037978]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"<p>A <b>domain of unknown function</b> (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.</p>","thumbnail":null}],"literature":{"PUB00037978":{"PMID":16948158,"ISBN":null,"volume":"65","issue":"3","year":2006,"title":"Crystal structure of an ORFan protein (TM1622) from Thermotoga maritima at 1.75 A resolution reveals a fold similar to the Ran-binding protein Mog1p.","URL":null,"raw_pages":"777-82","medline_journal":"Proteins","ISO_journal":"Proteins","authors":["Xu Q","Krishna SS","McMullan D","Schwarzenbacher R","Miller MD","Abdubek P","Agarwalla S","Ambing E","Astakhova T","Axelrod HL","Canaves JM","Carlton D","Chiu HJ","Clayton T","DiDonato M","Duan L","Elsliger MA","Feuerhelm J","Grzechnik SK","Hale J","Hampton E","Han GW","Haugen J","Jaroszewski L","Jin KK","Klock HE","Knuth MW","Koesema E","Kreusch A","Kuhn P","Morse AT","Nigoghossian E","Okach L","Oommachen S","Paulsen J","Quijano K","Reyes R","Rife CL","Spraggon G","Stevens RC","van den Bedem H","White A","Wolf G","Hodgson KO","Wooley J","Deacon AM","Godzik A","Lesley SA","Wilson IA."],"DOI_URL":"http://dx.doi.org/10.1002/prot.21015"}},"set_info":{"accession":"CL0946","name":"MucB_RseB_C"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":1,"interactions":0,"matches":20,"pathways":0,"proteins":20,"proteomes":20,"sets":1,"structural_models":{"alphafold":17},"structures":1,"taxa":45},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":4,"alignment:full":8},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":{"accession":"1vr8","name":"Crystal structure of GTP binding regulator (TM1622) from Thermotoga Maritima at 1.75 A resolution"}}}